ELISA FOXA3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:FKHH3 antibody; Fork head-related protein FKH H3 antibody; forkhead box A3 antibody; Forkhead box protein A3 antibody; Foxa3 antibody; FOXA3_ antibody; hepatic nuclear factor-3-beta antibody; hepatocyte nuclear factor 3 antibody; hepatocyte nuclear factor 3 gamma antibody; Hepatocyte nuclear factor 3-gamma antibody; HNF-3-gamma antibody; HNF-3G antibody; HNF3B antibody; HNF3G antibody; TCF-3G antibody; TCF3G antibody; Transcription factor 3G antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P55318 Immunogen:Recombinant Hepatocyte nuclear factor 3-gamma protein (220-336AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcription factor that is thoµght to act as a \'pioneer\' factor opening the compacted chromatin for other proteins throµgh interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regµLatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regµLation of neuronal-specific transcription. May be involved in regµLation of spermatogenesis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FOXA3 Research Areas:Epigenetics and Nuclear Signaling