ELISA DNAJC10 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Endoplasmic reticµLum disµLfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticµLum by catalyzing the removal of non-native disµLfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticµLum-associated degradation(ERAD) by reducing incorrect disµLfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disµLfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticµLum stress. Immunogen:DnaJ(Hsp40) homolog, subfamily C, member 10 Synonyms:ERDJ5 Observed MW:75-80 kDa Uniprot ID:Q8IXB1 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200 Gene ID:54431 Research Area:Metabolism