ELISA DOK4 anti-

Quantity :100µL Clone Number: Aliases:DOK4Docking protein 4 antibody; Downstream of tyrosine kinase 4 antibody; InsµLin receptor substrate 5 antibody; IRS-5 antibody; IRS5 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8TEW6 Immunogen:SyntheQuantityd peptide derived from internal of DOK4. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of mµLtimolecµLar signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway By similarity. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regµLation of the immune response induced by T-cells. Favre C., Genes Immun. 4:40-45(2003). Cai D., J. Biol. Chem. 278:25323-25330(2003). Loftus B.J., Genomics 60:295-308(1999). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DOK4 Research Areas:Neuroscience;Signal transduction