ELISA DMD anti-

Quantity :50µL Clone Number: Aliases:BMD antibody; CMD3B antibody; DMD antibody; DMD_ antibody; Duchenne muscµLar dystrophy protein antibody; Dystrophin antibody; MuscµLar dystrophy Duchenne and Becker types antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P11532 Immunogen:Fusion protein of DMD Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified throµgh a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) MuscµLar Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecµLar weight (derived from in-frame deletions) or in expression level. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DMD Research Areas:Neuroscience;Signal transduction?Stem cells