ELISA DOCK1 anti-

Quantity :100µL Clone Number: Aliases:180 kDa protein downstream of CRK antibody; Ced5 antibody; Dedicator of Cytokinesis 1 antibody; Dedicator of cytokinesis protein 1 antibody; DOCK 1 antibody; DOCK 180 antibody; DOCK1 antibody; DOCK1_ antibody; DOCK180 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14185 Immunogen:SyntheQuantityd peptide derived from internal of DOCK1. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1. Hasegawa H., Mol. Cell. Biol. 16:1770-1776(1996). Deloukas P., Nature 429:375-381(2004). Matsuda M., J. Biol. Chem. 271:14468-14472(1996). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DOCK1 Research Areas:Cancer;Cell biology;Metabolism;Signal transduction