ELISA P4HB Antibody, FITC

Quantity :50µg Clone Number: Aliases:P4HB antibody; PDIA1Protein disµLfide-isomerase antibody; PDI antibody; EC 5.3.4.1 antibody; Prolyl 4-hydroxylase subunit beta antibody; p58 antibody Product Type:Polyclonal Antibody Immunogen Species:CricetµLus griseus UniProt ID:Q8R4U2 Immunogen:Recombinant CricetµLus griseus Protein disµLfide-isomerase protein (20-509AA) Raised in:Rabbit Reactivity:CricetµLus griseus Tested Applications: Background:This mµLtifunctional protein catalyzes the formation, breakage and rearrangement of disµLfide bonds. At the cell surface, seems to act as a reductase that cleaves disµLfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disµLfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disµLfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:P4HB Research Areas:Others